Effects
If left untreated, the long-term effects of PNH can be serious and potentially life-threatening.
Blood clots and kidney failure are two significant causes of death in people with
PNH.3,13 In fact, venous or arterial thromboses account for approximately
40 percent to 67 percent of PNH-related deaths.3,12-15 Poor kidney function,
or renal insufficiency, is six times more prevalent in patients with PNH than in
the general population.16,17
Patients with PNH also suffer from severe quality-of-life issues, including severe
fatigue, abdominal pain, difficulty swallowing, erectile dysfunction and poor cognitive
function. These issues often force patients to modify their daily activity.6
Consequences of Hemolysis in PNH
